I have been involved in research in large number of areas of physiology and biophysics, including: capillary exchange, small intestinal circulation and absorption, blood-tissue exchange kinetics, membrane and ion channel biophysics, ethanol pharmacokinetics, and X-ray crystallography. My current area of research interest is in pharmacokinetics, which makes use of my background in these varied fields. I recently developed PKQuest (www.pkquest.com), a new pharmacokinetic software program. I am now focused on the further development of this program and its application to a number of pharmacokinetic research areas.

Pharmacokinetic Publications:

Levitt DG. PKQUEST: Capillary Permeability Limitation and Plasma Protein Binding - Application to Human Inulin, Dicloxacillin and Ceftriaxone Pharmacokinetics. BMC Clin Pharmacol. 2002 Sep 26

Levitt DG. PKQuest: volatile solutes - application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics.BMC Anesthesiol. 2002 Aug 15;2(1):5.

Levitt DG. PKQuest: measurement of intestinal absorption and first pass metabolism - application to human ethanol pharmacokinetics.BMC Clin Pharmacol. 2002 Aug 15;2(1):4.

Levitt DG. PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol. BMC Clin Pharmacol. 2002 Aug 15;2(1):5.

Levitt, DG. The Use of a Physiologically Based Pharmacokinetic Model to Evaluate Deconvolution Measurements of Systemic Absorption. BMC Clin Pharmacol. 2003, 3:1 (19 Mar 2003).

Levitt, DG. The Pharmacokinetics of the Interstitial Space in Humans. BMC Clin Pharmacol. Submitted.

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